We are blessed to continue to draw on a history of excellence in Catholic education dating back to our founding. Antonian College Preparatory High School provides a holistic education encompassing spiritual, intellectual, social, emotional, and physical growth.

Antonian was founded as an all-boys Catholic high school in 1964 by the Archdiocese of San Antonio with the support of the pastors from twelve northside parishes and staffed by the Brothers of the Christian Schools. The school's motto was a statement of purpose – to build better men. Through the various functions and facilities of Antonian, each student was given endless opportunities to discover truth. Each understands oneself and the world in this endeavor to make this discovery. That understanding enabled students to become better Christians and more intelligent members of society. 

Antonian retains many innovative practices attributed to St. John Baptiste De La Salle, including integrating religious instruction with academic subjects, well-prepared teachers with a sense of vocation and mission, and the involvement of parents. Originally a school for boys, Antonian transitioned to a co-educational school in 1989.

Antonian students have been supported by over 50 years of rich history and traditions. Preparing students academically, socially, and emotionally for higher education and life demands an environment reflective of the real world. The real world is comprised of men and women, and Antonian graduates are prepared to interact and work with members of the opposite sex both in college and classrooms and in the workplace. This Antonian dynamic empowers students to grow as individuals and community members. Committed to Catholic education, Antonian College Preparatory High School remains the largest Catholic high school in the Archdiocese of San Antonio.